The R library drfit is
routinely used in our Department for analysing our cytotoxicity, enzyme
inhibition and some ecotoxicity data, e.g. from tests with Lemna minor,
Vibrio fischeri or growth inhibition assays with plants. The package is
hosted on CRAN since July 21, 2004.
Some time later, the drc package appeared on CRAN, which is now
much more powerful and better maintained than my package. However,
drfit still does an excellent job in automated dose-response
evaluation of the large amounts of data in the UFT databases.
It is also different from drc as in drfit the concentration
response data are first normalised between the values of the negative and the
positive controls, so the zero and full response levels are not fitted to the
data but taken from prior information.
drfit.php last modified January 29, 2011